Project Lead: Christian Ernst Heinrich Boehler
Authors: Christian Ernst Heinrich Boehler, Sarah
Publication: December 2020
Language: English (with German summary)
Recent evidence on the effectiveness of lung cancer screening with low dose computed tomography (LDCT), such as the National Lung Screening Trial (NLST) or the Dutch-Belgian Randomized Lung Cancer Screening Trial (NELSON), seems to confirm a potential relative lung cancer mortality reduction (although not in overall mortality) from the LDCT-screening. Since then, a considerable body of new evidence also emerged on the cost-effectiveness of LDCT-screening for lung cancer. In this context, the present systematic review aimed to provide an update of the evidence on the cost-effectiveness, cost-utility and budget impact of LDCT lung cancer screening in adult persons without confirmed or suspected lung cancer but at elevated risk, with a special focus on the health economic methodologies.