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                                      Welcome to the homepage of AIHTA!

                                      AIHTA is an academic non-profit institute. At our website we wish to present our research and give support for health care decision-making. Here all of our reports are available for free. For further information please contact the AIHTA team.

                                      In the News section you will find our most recent publications: newsletter, project-reports etc. Previous reports you might find via Research areas, Research projects and Repository.

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                                      Newsletter

                                      Newsletter Archive

                                      Newsletter November 2013 | Nr. 122

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                                      Announcement

                                      Evidence requirements for the authorization and reimbursement of high-risk medical devices in the USA, Europe, Australia and Canada: An analysis of seven high-risk medical devices

                                      This research first explored the authorization systems for high-risk medical devices in four selected regions (USA, Canada, Australia and Europe) of the western world. Secondly, it analyzed the clinical evidence accessible at time of market approval and decision support (HTA) for reimbursement for seven selected high-risk medical devices. The results support a change in the European authorization system towards a transparent and evidence-based regulation process: All seven medical devices have been approved in the European Union through an appointed Notified Body, only four by the Australian TGA, one each by the US-American FDA and by the Canadian TPD. In comparison to the other three regulatory systems, the number of approved devices in Europe is high, esp. if additionally taken into consideration that four further devices were also assessed by the FDA, but either rejected or not approved for general use.

                                      Publication: LBI-HTA Project report No. 73: https://eprints.aihta.at/1017

                                      Contact: Claudia Wild

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                                      Announcement

                                      Occupational therapy in children and adolescents. Literature review on indications, utilisation and recommendations

                                      The frequency of prescriptions and underlying indications of occupational therapy (OT) in children and adolescents in Austria are unclear. The aim of the project was to identify fields of application and recommendations for OT as well as information on the frequency of prescriptions from (German) health insurance reports. We included 24 review articles, 20 guidelines and 4 health reports.

                                      The results show that among many other indication areas CNS-disorders, developmental delays and ADHD were mentioned most often. Detailed, indication-specific information concerning prescription of OT for children and young people cannot be found.

                                      Publication: LBI-HTA Project report No. 70: https://eprints.aihta.at/1016

                                      Contact: Johanna Breuer

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                                      213

                                      Announcement

                                      Horizon Scanning in Onkology - Reports

                                      We are pleased to introduce our new HSO report.

                                      DSD HSO No. 42
                                      Dabrafenib (Tafinlar®) in previously untreated subjects with BRAF mutation-positive advanced (stage III) or metastatic (stage IV) melanoma

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                                      Announcement

                                      Identification of ineffective interventions and technologies Existing models and their implementation

                                      Due to rising health care costs, limited resources and the fact that many interventions and technologies currently in use have never been systematically assessed regarding effectiveness, cost-effectiveness and safety, active identification of ineffective interventions and technologies is gaining importance.

                                      This systematic analysis of 8 already implemented models for the identification of ineffective interventions and technologies highlights existing commonalities between these models as well as general challenges that arise from the development and implementation of such models.

                                      Publication: LBI-HTA Projektbericht Nr. 68: https://eprints.aihta.at/1014

                                      Contakt: Julia Mayer

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                                      Event archive

                                      20131120-091711

                                      Event

                                      First LBG Meeting for Health Sciences 2013

                                      2. December 2013

                                      9:00-21:00

                                      Haus der Industrie, Schwarzenberg Platz 4

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                                      Announcement

                                      Mental Health Rehabilitation for Children and Adolescents – Systematic overview of evaluation outcomes and instruments

                                      ‘Mental Health Rehabilitation’ (MHR) for children and adolescents cover a wide range of psychosocial measures. The primary project aim was to collect and analyse evaluation indicators and instruments for MHR-programmes for children and adolescents. Within the context of a systematic literature search, we identified 6 studies involving 5 evaluation indicators (clinical symptoms, quality of life, functionality, rehabilitation process and rehabilitation satisfaction). In total, we described 21 instruments for outcome assessment; most of the instruments have been used in assessments across various mental health disorders affecting children and adolescents (‘generic tools’).
                                       
                                      Publication: LBI-HTA Project report No. 67: https://eprints.aihta.at/1012/

                                      Contact: Roman Winkler
                                       

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                                      Announcement

                                      Zostavax® for the prevention of herpes zoster and postherpetic neuralagia. Pilot assessment using the draft HTA Core Model for Rapid Relative Effectiveness Assessment. Pilot-ID: WP-SA-1

                                      Herpes Zoster (Shingles) primarily occurs in people over 50 years old. The disease is hardly lethal, however, it is often associated with long-term pain (postherpetic neuralgia) and decreased quality of life. Since 2006, a vaccine against Herpes Zoster (Zostavax®) has been licensed for persons aged 50+. Completed studies so far have shown that vaccination decreases Herpes Zoster incidence, however, the benefit for patients in terms of quality of life or long-term pain is unclear. Moreover, the vaccine’s efficacy in terms of Herpes Zoster incidence decreases substantially with age. Overall mortality and hospital admissions on a population level won’t be reduced with vaccination. Because safety data have indicated an increased risk for severe adverse events in people over 80 years of age after vaccination, members of this age group should rigorously weigh benefit against risks.

                                      Publication: Decision Support Document Nr. 73: https://eprints.aihta.at/1013/

                                      Contact: Ingrid Zechmeister-Koss

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                                      Newsletter

                                      Newsletter Archive

                                      Newsletter October 2013 | Nr. 121

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                                      212

                                      Announcement

                                      Horizon Scanning in Onkology - Reports

                                      We are pleased to introduce two new HSO reports.

                                      DSD HSO No. 39
                                      Pomalidomide (Pomalyst®) for the ? 3rd-line therapy of patients with relapsed and refractory multiple myeloma

                                      DSD HSO No. 40
                                      Regorafenib (Stivarga®) for heavily pretreated patients with metastatic colorectal cancer (mCRC)

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