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                                Current & archive

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                                Social Return on Investment: Outcomes, Methods, and Economic Parameters

                                Social Return On Investment measures the social „value for money“ of an intervention. In our project, though, we are providing an overview of studies measuring the return on investment of 15 health-related interventions from the societal perspective. The studies have shown that all interventions are worth the investment. Thus, the savings are higher than the costs of the interventions. The highest returns can be expected in the areas of “crime” and “income”.

                                Publication: LBI-HTA Project report No. 96: https://eprints.aihta.at/1142/

                                Contact: Stefan Fischer

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                                Tavi-fotolia-76356839-m3

                                Percutaneous aortic valve replacement in Austria (Part II): Data analysis

                                A secondary analysis of reimbursement data (DRG-data) from public hospitals was conducted in order to determine how the Aortic Valve Replacement was implemented 2009-2016, either percutaneously (TAVI) or surgically (SAVR), in the Austrian healthcare system. For the period 2009 and 2016, in total 4,338 TAVI and 16,439 surgical aortic valve replacements (SAVR) were carried out. During this period the data show a constant rise in TAVI and a slight fall in SAVR use.  The analysed data show a rate of 107 TAVI per million inhabitants in Austria. 

                                Publication: LBI-HTA Project report No. 95b: https://eprints.aihta.at/1141/

                                Contact: Martin Robausch

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                                2131

                                Horizon Scanning in Onkology - Reports

                                We are pleased to introduce our new HSO report.

                                DSD HSO No. 74
                                Midostaurin with standard chemotherapy in FLT3-Positive Acute Myeloid Leukaemia 

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                                Tavi-fotolia-76356839-m2

                                Transcatheter Aortic Valve Implantation Part I: A systematic review of health economic evaluations

                                For several years, the high-cost Transcatheter Aortic Valve Implantation (TAVI) has been a less invasive alternative to surgery for patients. The aim of the present work was to evaluate the health-economic evaluations of TAVI for inoperable patients and operable patients with high or intermediate surgical risk within a systematic review. The results showed that, TAVI was cost-effective compared to Medical Management in inoperable patients, whereas TAVI compared to Standard Management in inoperable patients and to Surgical Aortic Valve Replacement in patients with high surgical risk resulted in controversial results. 

                                Publication: LBI-HTA Project report No. 95: https://eprints.aihta.at/1139

                                Contact: Sarah Wolf

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                                2130

                                Horizon Scanning in Oncology - Reports

                                We are pleased to introduce our new HSO report.

                                DSD HSO No. 73
                                Regorafenib indicated  as monotherapy for the treatment of adult patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib

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                                2129

                                Horizon Scanning in Onkology - Reports

                                We are pleased to introduce our two new HSO reports.

                                DSD HSO No. 72
                                Abemaciclib (Verzenio®) in combination with fulvestrant for treatment of HR-positive, HER2-negative advanced breast cancer (ABC)

                                DSD HSO No. 71
                                Olaparib (Lynparza®) in patients with BRCA-mutated metastatic breast cancer

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                                Sponsoring of Patientinitiatives in Austria 2016. Update of the Systematic Analyses 2015 and 2014

                                As part of the professionalization of patients organizations and the expansion of their activities (eg. awareness campaigns, advisory services for patients and their relatives, etc.) the need for financial resources is also increasing. This need is often covered by pharmaceutical and medical device manufacturers. This update analyzed the extent of financial support for patient organizations from pharmaceutical companies in Austria in 2016. 40 of 118 PHARMIG member companies have declared donations to patient organization for the year 2016. A total sum of € 1.435.059 in grants to patient initiatives were reported by the PHARMIG member companies. Most grants (72%) were given to initiatives in the field of Oncology & Hematology, Neurology, Lung, Hemophilia, and Rheumatology.

                                Altogether the increase in disclosure in comparison to 2015 was much lower. The total sum of contributions even decreased by almost 20% compared to 2015.

                                Publication: Rapid Assessment Nr. 7b/2. Update 2017: https://eprints.aihta.at/1132

                                Contact: Philipp Petersen

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                                2413

                                Evaluation of individual medical procedures 2017 - Reports

                                We are pleased to introduce our new reports.

                                Decison Support Documents 2017

                                • DSD 104: Electric stimulation therapy (EST) in patients with gastroesophageal reflux disease (GERD)
                                  https://eprints.aihta.at/1128
                                • DSD 105: Prostate artery embolisation for benign prostatic hyperplasia
                                  https://eprints.aihta.at/1118
                                • DSD 106: Extracorporeal cytokine haemadsorption therapy in patients with sepsis or SIRS
                                  https://eprints.aihta.at/1129
                                • DSD 107: Repetitive transcranial magnetic stimulation for treatment-resistant major depression
                                  https://eprints.aihta.at/1130
                                • DSD 108: Radiofrequency ablation for metastatic spinal lesions
                                  https://eprints.aihta.at/1131

                                +2 Updates:

                                • DSD 21/Update 2017: Percutaneous disc volume reduction – chemonucleolysis
                                  https://eprints.aihta.at/1126
                                • DSD 97/Update 2017: Leadless pacemakers for right ventricle pacing
                                  https://eprints.aihta.at/1127

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                                Sponsoring of Patientinitiatives in Austria 2015. Update of the Systematic Analysis 2014

                                As part of the professionalization of patients organizations and the expansion of their activities (eg. awareness campaigns, advisory services for patients and their relatives, etc.) the need for financial resources is also increasing. This need is often covered by pharmaceutical and medical device manufacturers. This update analyzed the extent of financial support for patient organizations from pharmaceutical companies in Austria in 2015. 36 of 116 PHARMIG member companies have declared donations to patient organization for the year 2015. A total sum of € 1.724.683 in grants to patient initiatives were reported by the PHARMIG member companies. Most grants (68%) were given to initiatives in the field of Oncology & Hematology, Neurology, Lung, Hepatitis, and Rheumatology.

                                Altogether there was a significant increase in disclosure in comparison to 2014. Both the number of pharmaceutical companies that declared financial contributions and the total sum of contributions has risen by 50%.

                                Publication: Rapid Assessment No. 7b/1. Update 2017: https://eprints.aihta.at/1125/

                                Contact: Philipp Petersen

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                                2128

                                Horizon Scanning in Onkology - Reports

                                We are pleased to introduce our two new HSO reports.

                                DSD HSO No. 70
                                Pembrolizumab (Keytruda®) as second-line treatment for patients with advanced urothelial carcinoma (UC)

                                DSD HSO No. 69
                                Ceritinib (Zykadia®) as first-line therapy for patients with advanced ALK-positive non-small cell lung cancer

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