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News
Welcome to the homepage of AIHTA!
AIHTA is an acadmic non-profit institute. At our website we wish to present our research and give support for health care decision-making. Here all of our reports are available for free. For further information please contact the AIHTA team.
In the News section you will find our most recent publications: newsletter, project-reports etc. Previous reports you might find via Research areas, Research projects and Repository.
Announcement
Horizon Scanning in Oncology - Fact Sheets
We are pleased to introduce our four new HSO Fact Sheets.
Fact Sheet No. 67
Pembrolizumab (Keytruda) in combination with Lenvatinib (Kisplyx) for the firstline treatment of advanced renal cell carcinoma (RCC)
Fact Sheet No. 68
Pembrolizumab (Keytruda) in combination with Lenvatinib (Kisplyx) for the treatment of advanced or recurrent endometrial carcinoma (EC)
Fact Sheet No. 69
Amivantamab (Rybrevant) as monotherapy for the treatment of patients with advanced non-small cell lung cancer (NSCLC)
Fact Sheet No. 70
Sacituzumab govitecan (Trodelvy) as monotherapy for the treatment of patients with unresectable or metastatic triple-negative breast cancer (mTNBC)
Announcement
Covid-19: HSS/ Horizon Scanning Living Document (v18 October/November 2021)
The establishment of a HSS/ Horizon Scanning System for Covid19 interventions has the intentions of informing health policy makers at an early stage which interventions (vaccinations and drugs) are currently undergoing clinical trials and to monitor them over the next few months in order to support evidence-based purchasing if necessary. The products are monitored with regard to the status of the clinical studies up to approval and finally evaluated for their benefit and harm.
All work steps are conducted in close international (European) cooperation.
Publications:
- Policy Brief No. 002: http://eprints.aihta.at/1234/
Contact: Claudia Wild
Announcement
Long COVID care pathways: a systematic review
Due to the expected growing number of long COVID cases and the associated increasing average sick leave durations, it not only places a burden on the patients and their families but also the wider economy, in particular, the workforce. The present systematic review aimed to support preparations and adjustments in the long COVID care planning in Austria by giving (1) an overview of recommendations about long COVID care pathways for adult patients as well as (2) examples of already existing care structures in selected European countries.
Publlication: HTA Project Report No. 135b: https://eprints.aihta.at/1342
Contact: Sarah Wolf
Announcement
Nivolumab in malignant melanoma: contrasting the evidence from the pivotal trials with the real world evidence (RWE)
Nivolumab is an anti-PD1 checkpoint inhibitor used in patients with advanced malignant melanoma. The aim of this project was to evaluate the real world evidence from observational studies on Nivolumab for the treatment of malignant melanoma and to contrast the results with the evidence from pivotal RCTs. As a result of the comparison, there was good concordance between the outcomes of the included real-world studies and those of the pivotal RCTs across various lines of therapy, with slightly lower response rates.
Publication: HTA Project report No. 140: https://eprints.aihta.at/1341
Contact: Claudia Wild
Newsletter
Note: this content is only available in German.
Inhalt
- Editorial: Belgischer HTA Bericht analysiert Aufwand und Ergebnis von Onkologika in 12 Tumorerkrankungen (2004 – 2017)
- Versorgungsforschung in der Onkologie: Immuntherapie bei NSCLC
- Versorgungsforschung in der Onkologie: Nivolumab bei Melanom
- DNA-Stuhltest zur Früherkennung von Darmkrebs – Update der Evidenz
- Zweitmeinungen bei chirurgischen Verfahren
- Termine
- Themen-Vorschau
Announcement
Horizon Scanning in Oncology - Fact Sheets
We are pleased to introduce our five new HSO Fact Sheets.
Fact Sheet No. 60
Zanubrutinib (Brukinsa®) as monotherapy for the treatment of patients with waldenström’s macroglobulinaemia (WM)
Fact Sheet No. 62
Ripretinib (Qinlock®) for the treatment of patients with advanced gastrointestinal stromal tumour (GIST)
Fact Sheet No. 64
Pembrolizumab (Keytruda®) in combination with chemotherapy for the treatment of locally recurrent unresectable or metastatic triple-negative breast cancer (TNBC)
Announcement
Stool DNA testing for colorectal cancer (CRC) screening
Colorectal Carcinoma (CRC) is the third most frequent cancer type, with an incidence and prevalence of approximately 4,800 and 40,000 cases respectively each year in Austria. Multi-target stool DNA (MT-sDNA) testing is a novel non-invasive screening test that may be able to supplement or replace established stool tests by analysing (stool-based) tumour DNA. In this policy brief, the latest available evidence with regard to the clinical benefits and harms of MT-sDNA tests is summarized.
Publication: Policy Brief No. 011: https://eprints.aihta.at/1335
Contact: Gregor Goetz
Newsletter
Note: this content is only available in German.
Inhalt
- Editorial: Nicht-Interventionelle Studien (NIS) in Österreich
- Elterntraining bei Kindern mit Aufmerksamkeitsdefizit- und Hyperaktivitätsstörung (ADHS)
- Long-Covid: Häufigkeit und mögliche Risikofaktoren
- Roboterunterstützte Chirurgie in der Gynäkologie
- Andexanet alfa zur Umkehrung der Gerinnungshemmung von Rivaroxaban oder Apixaban
- Termine
- Themen-Vorschau
Announcement
Covid-19: HSS/ Horizon Scanning Living Document (v17 August/September 2021)
The establishment of a HSS/ Horizon Scanning System for Covid19 interventions has the intentions of informing health policy makers at an early stage which interventions (vaccinations and drugs) are currently undergoing clinical trials and to monitor them over the next few months in order to support evidence-based purchasing if necessary. The products are monitored with regard to the status of the clinical studies up to approval and finally evaluated for their benefit and harm.
All work steps are conducted in close international (European) cooperation.
Publications:
- Policy Brief No. 002: http://eprints.aihta.at/1234/
Contact: Claudia Wild
Announcement
Health Services Research in Oncology: Patients with Non-Small Cell Lung Cancer (NSCLC) Treated with Anti-PD-1/PD-L1 Therapy in Real-World Practice
Real World Evidence (RWE) complements the data of randomised clinical trials, that are based on selected, homogeneous patient collectives and a limited study duration, with long-term data from clinical practice. As there has been no evaluation of immunotherapy in everyday care in Austria to date, a retrospective pilot study was conducted in six Austrian hospitals on the efficacy and safety of anti-PD-1/PDL1 monotherapy in patients with NSCLC using routine data.
Publication: HTA Project report No. 126: https://eprints.aihta.at/1227
Contact: claudia.wild@aihta.at; sabine.geiger-gritsch@tirol-kliniken.at
