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News
Welcome to the homepage of AIHTA!
AIHTA is an academic non-profit institute. At our website we wish to present our research and give support for health care decision-making. Here all of our reports are available for free. For further information please contact the AIHTA team.
In the News section you will find our most recent publications: newsletter, project-reports etc. Previous reports you might find via Research areas, Research projects and Repository.
Announcement
Vaccination against human papillomavirus (HPV). Decision-aid for young women and girls
In 2008 the German AOK-Bundesverband commissioned the LBI-HTA to develop a decision-aid on the vaccination against Human Papillomavirus (HPV) for young women and girls (online since June 2009). After smaller updates in 2010 and 2011, the updated, completely revised and partly new structured decision-aid went online in March 2015 (www.hpv-entscheidungshilfe.de).The first part of the decision aid contains information about the virus and HPV related diseases. The second part of the decision aid informs about the HPV-vaccine(s). Finally, the third part of the decision aid summarises information of parts I and II: eleven short information blocks can be rated according to the relevance for the decision (mainly pro or mainly contra vaccination or of no influence). In the present project report online contents are available in paper form for the first time. Hence, we were able to add country specific data for Austria and provide further, more detailed information (which has not been included in the online version due to complexity).
Publication: Decision Support Document No. 79: https://eprints.aihta.at/1050
Contact: Brigitte Piso
Announcement
Horizon Scanning in Onkology - Reports
We are pleased to introduce our new HSO report.
DSD HSO No. 50
Nivolumab (Opdivo®) as single-agent first-line therapy for unresectable or metastatic melanoma
Project / ,
HTA Strategy for Lithuania
Project leaders: /page/claudia-wild/en
Project team: /page/claudia-wild/en, /page/tarquin-mittermayr/en
Duration: February 2015 - July 2015
Publication: HTA Decision Support Document No. 90a: https://eprints.aihta.at/1064/
Announcement
Hadron therapy in children: evidence synthesis for 15 paediatric tumours. Report based on Belgian (KCE) HTA report
A Belgian KCE-Assessment analysed – as an update of the 2007 report – the evidence for hadron therapy (proton and carbon ions) in 15 paediatric indications. Since 2015 the Austrian MedAustron started operating and the first patients are treated, the LBI -HTA has been involved in the Belgian report as external expert. Now the LBI -HTA wrote – due to the regional relevance – a German summary of the Belgian report.
In the assessment 21 clinical studies (non-randomized, non-controlled and mostly retrospective) were found. All studies showed serious methodological flaws. The conclusion therefore is that to date clinical data on PBT in all paediatric cancers under study are lacking as well as critical information on long-term effectiveness and harms.
Prospective comparative clinical trials in the field are urgently needed.
Publication: Decision Support Document Nr. 88: https://eprints.aihta.at/1049
Contact: Claudia Wild
Announcement
Vasoprotectives: Efficacy and safety of capillary stabilising agents for venous insufficiency or haemorrhoidal diseases
The systematic review assessed the efficacy and safety of a treatment of chronic venous insufficiency (CVI) and haemorrhoidal diseases (HD) with capillary stabilising agents that are listed in the Austrian Code of Reimbursement.
A total of 56 studies were included for a data synthesis.
The majority of studies have shown that the symptoms and signs of CVI and HD can be reduced slightly with the agents (mostly when compared to placebo). Only minor side effects occurred.
However, the strength of the evidence of nearly all identified studies is low. Therefore, we cannot draw a final conclusion on the efficacy of capillary stabilising agents for the treatment of CVI and HD.
Publication: LBI-HTA Project report No. 79: https://eprints.aihta.at/1047
Contact: Stefan Fischer
