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AIHTA is an acadmic non-profit institute. At our website we wish to present our research and give support for health care decision-making. Here all of our reports are available for free. For further information please contact the AIHTA team.
In the News section you will find our most recent publications: newsletter, project-reports etc. Previous reports you might find via Research areas, Research projects and Repository.
Announcement
Horizon Scanning in Onkology - Reports
We are pleased to introduce our two new HSO reports.
DSD HSO No. 65
Ribociclib in combination with letrozole for the first-line therapy of HR-positive, HER2-negative recurrent or metastatic breast cancer
DSD HSO No. 66
Neratinib for the treatment of patients with HER2-positive breast cancer after trastuzumab-based adjuvant therapy
Newsletter
Announcement
Re-orientation of the Austrian parent-child preventive care programme. Part XII: Economic evaluation of selected screenings during pregnancy
In this report, we conducted an economic analysis of three screenings during pregnancy: testing of TSH as screening for hypothyroidism, urine culture as screening for asymptomatic bacteriuria and ultrasound screening for foetal anomalies.
Over a three years period, the screening for hypothyroidism would save 2 million euros due to prevented preterm births. The costs for the screening for bacteriuria using urine culture are 1.17 million euros and the costs for the ultrasound screening would cost 337,800 euros, when 5 % of all pregnant women would be screened.
Publlication: LBI-HTA Project report No. 91: https://eprints.aihta.at/1112/
Contact: Stefan Fischer
Announcement
Horizon Scanning in Onkology - Reports
We are pleased to introduce our new HSO report.
DSD HSO No. 63
Ixazomib (Ninlaro®) in combination with lenalidomide and dexamethasone for the treatment of multiple myeloma (MM)
Newsletter
Announcement
Supply mandates
The definition of the “Best point of service (BPoS)” for all healthcare settings is a primary goal and shall be re-thought and set by the Austrian health reform. Against this background, part I of this report is based on definitions, models and approaches towards the potential content of a BPoS. The BPoS for the outpatient area at the conceptual level is discussed. In Part II, two concrete health interventions are presented alongside the evidence of the effectiveness and safety. Furthermore, the analysis shall involve organisational information regarding the service provision of a BPoS (using the “organisational domain” of the EUnetHTA core model).
Publication: LBI-HTA Project report No. 88: https://eprints.aihta.at/1110/
Contact: Brigitte Piso
Announcement
Wearable cardioverter-defibrillator (WCD) therapy in primary and secondary prevention of sudden cardiac arrest in patients at risk
Sudden cardiac arrest (SCA) is the most common cause of death in patients with coronary artery disease. In Europe, there are about 350 000 out of hospital SCAs per year. Mostly, ventricular tachycardia and ventricular fibrillation are the underlying aetiology of SCA, which is claimed to be successfully treated by a novel defibrillation therapy, a wearable cardioverter defibrillator (WCD).
This assessment, performed within the „European Network for Health Technology Assessment“ (EUnetHTA) Joint Action 3, aimed to provide valid data on clinical effectiveness and safety of the WCD. Furthermore, the project intended to elicit patients’ views on aspects regarding their cardiac disease and the WCD therapy as well as to identify neglected outcomes.
According to the published data, no statement can be made about the device effectiveness – further research is needed. Studies suggest that the WCD could be a relatively safe intervention in the short to medium term. However, more data and more adequate reporting of (serious) adverse events are needed in order to establish the device safety. In particular, more data is needed for specific risk stratification of high risk patients in order to further narrow down the wide range of indications for WCD use.
Publication: Decision Support Document No. 103: https://eprints.aihta.at/1109/
Contact: Sabine Ettinger
Announcement
Outpatient cardiac rehabilitation. Part VII: economic evaluation
In addition to the results of the prospective multicentre cohort study on the effectiveness of the outpatient cardiac phase III rehabilitation programme (see part VI), the aim of this report was to compare the costs that occur due to the treatment of cardiovascular diseases of patients who underwent an outpatient cardiac phase III rehabilitation programme (intervention group) and patients who did not receive this phase III (control group).
The data of a total of 164 patients was analysed for this report. On average, the total costs that occurred for patients in the control group were 2,900 euros per patient and 5,099 euros per patient in the intervention group.
Publication: LBI-HTA Project report No. 89: https://eprints.aihta.at/1102/
Contact: Stefan Fischer